Cannabinoids as therapeutic agents. PCCG-4 is a research drug which acts as a selective antagonist for the group II metabotropic glutamate receptors (mGluR2/3), with slight selectivity for mGluR2 although not sufficient to distinguish mGluR2 and mGluR3 responses from each other. LY-307,452 is a drug used in neuroscience research, which was among the first compounds found that acts as a selective antagonist for the group II metabotropic glutamate receptors (mGluR2/3), and was useful in early studies of this receptor family, although it has largely been replaced by newer drugs such as LY-341,495. However, the role of these interactions and how they result in the cannabinoid high has yet to be scientifically validated. It is a multidisciplinary branch of biology that combines physiology, anatomy, molecular biology, developmental biology, cytology, mathematical modeling and psychology to understand the fundamental and emergent properties of neurons and neural circuits. "Study on the phase I metabolism of novel synthetic cannabinoids, APICA and its fluorinated analogue". Thorough independent research and harm reduction practices are strongly advised if choosing to use this substance. CDPPB is a drug used in scientific research which acts as a positive allosteric modulator selective for the metabotropic glutamate receptor subtype mGluR5. For the cannabinoid drug, see, InChI=1S/C10H12NO5P/c11-10(9(12)13)4-3-6-5-7(17(14,15)16)1-2-8(6)10/h1-2,5H,3-4,11H2,(H,12,13)(H2,14,15,16), 1-Amino-5-phosphonoindan-1-carboxylic acid. 1-Amino-5-phosphonoindan-1-carboxylic acid (APICA) is a drug that is used in neuroscience research. [1][2][3][4][5], This article is about the metabotropic glutamate receptor antagonist. Neuroscience is the scientific study of the nervous system. Cannabinoids for treatment of chronic non-cancer pain; a systematic review of randomized trials |, Causal association between cannabis and psychosis: examination of the evidence - The British Journal of Psychiatry Jan 2004, 184 (2) 110-117 |, “Spice” Girls: Synthetic Cannabinoid Intoxication - The Journal of Emergency Medicine Volume 40, Issue 3, March 2011, Pages 296–299 (ScienceDirect) |, A Teenager With Agitation: Higher Than She Should Have Climbed - Pediatric Emergency Care: June 2010 - Volume 26 - Issue 6 - pp 462-465 |, The Misuse of Drugs Act 1971 (Amendment) Order 2016 (Legislation.gov.uk) |, Synthetic cannabinoid § Toxicity and harm potential, Research chemicals § Toxicity and harm potential, 2NE1 (N-adamantyl-1-pentylindole-3-carboxamide) Drug Info (Drugs-Forum), https://www.ncbi.nlm.nih.gov/pubmed/25921407, https://doi.org/10.1007/s11419-012-0136-7, http://www.emcdda.europa.eu/topics/pods/synthetic-cannabinoids, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3715837/, https://www.ncbi.nlm.nih.gov/pubmed/25428705, http://science.howstuffworks.com/marijuana4.htm, http://onlinelibrary.wiley.com/doi/10.1111/j.1526-4637.2009.00703.x/abstract, http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2125.2011.03970.x/abstract, http://bjp.rcpsych.org/content/184/2/110.short, http://www.sciencedirect.com/science/article/pii/S0736467910008802, http://journals.lww.com/pec-online/Abstract/2010/06000/A_Teenager_With_Agitation__Higher_Than_She_Should.16.aspx, http://www.sfda.gov.cn/WS01/CL0056/130753.html, "Achtundzwanzigste Verordnung zur Änderung betäubungsmittelrechtlicher Vorschriften", "Verordnung des EDI über die Verzeichnisse der Betäubungsmittel, psychotropen Stoffe, Vorläuferstoffe und Hilfschemikalien", http://www.legislation.gov.uk/uksi/2016/1109/made, https://psychonautwiki.org/w/index.php?title=APICA&oldid=142122, Creative Commons Attribution-ShareAlike 4.0 International, "You are the universe experiencing itself.".
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